About Zinc finger protein 814
Zinc finger protein 814 (ZNF814) is a protein
from Homo sapiens identified by UniProt accession
B7Z6K7, 855 residues long.
MolForge cross-references it against 0 known binders and
12 disease associations.
Target properties
| Protein name | Zinc finger protein 814 |
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| UniProt accession | B7Z6K7 |
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| Gene | ZNF814 |
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| Organism | Homo sapiens |
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| Length | 855 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (12)
Diseases linked to this target (Open Targets).
- gastric adenocarcinoma · score 0.22
- mean corpuscular volume · score 0.03
- vitamin D measurement · score 0.02
- total cholesterol measurement · score 0.02
- IGA glomerulonephritis · score 0.01
- hepatocellular carcinoma · score 0.01
- renal cell carcinoma · score 0.00
- nonpapillary renal cell carcinoma · score 0.00
- hemoglobin measurement · score 0.00
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-B7Z6K7-F1 | alphafold | PREDICTED | 69.32 | — |
Amino-acid sequence (855 residues)
MAAAATLRLS AQGTVTFEDV AVNFTWEEWN LLSEAQRCLY RDVTLENLAL ISSLGCWCGV EDEAAPSKQS IYIQRETQVR TPMAGVSPKK AHPCEMCGPI LGDILHVADH QGTHHKQKLH RCEAWGNKLY DSGNFHQHQN EHIGEKPYRG SVEEALFAKR CKLHVSGESS VFSESGKDFL PRSGLLQQEA SHTGEKSNSK TECVSPIQCG GAHYSCGESM KHFSTKHILS QHQRLLTREE CYVCCECGKS FSKYASLSNH QRVHTEKKHE CGECGKSFSK YVSFSNHQRV HTEKKHECGE CGKSFSKYVS FSNHQRVHTG KRPYECGECG KSFSKYASFS NHQRVHTEKK HYECGECGKS FSKYVSFSNH QRVHTGKRPY ECGECGKSFS KYASFSNHQR VHTDKKHYEC GECGKSFSQK SSLIQHQRFH TGEKPYGCEE CGKSFSSEGH LRSHQRVHAG ERPFKCGECV KSFSHKRSLV HHQRVHSGER PYQCGECGKS FSQKGNLVLH QRVHTGARPY ECGECGKSFS SKGHLRNHQQ IHTGDRLYEC GECGKSFSHK GTLILHQRVH PRERSYGCGE CGKSFSSIGH LRSHQRVHTG ERPYECGECG KSFSHKRSLV HHQRMHTGER PYKCGDCGKS FNEKGHLRNH QRVHTTERPF KCGECGKCFS HKGNLILHQH GHTGERPYVC RECGKLFKKK SHLLVHQRIH NGEKPYACEA CQKFFRNKYQ LIAHQRVHTG ERPYECNDCG KSFTHSSTFC VHKRIHTGEK PYECSECGKS FAESSSFTKH KRVHTGEKPY ECSECGKSFA ESSSLTKHKR VHTGEKPYKC EKCGKLFNKK SHLLVHQSSH WRKAI
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