Putative transmembrane protein INAFM1 (INAFM1)

Homo sapiens — UniProt C9JVW0

Gene: INAFM1Homo sapiensSwissProt reviewed

About Putative transmembrane protein INAFM1

Putative transmembrane protein INAFM1 (INAFM1) is a protein from Homo sapiens identified by UniProt accession C9JVW0, 142 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.

Target properties

Protein namePutative transmembrane protein INAFM1
UniProt accessionC9JVW0
GeneINAFM1
OrganismHomo sapiens
Length142 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (13)

Diseases linked to this target (Open Targets).

  • FEV/FVC ratio · score 0.27
  • leukocyte count · score 0.26
  • neutrophil count · score 0.23
  • body height · score 0.18
  • eosinophil count · score 0.17
  • hemoglobin measurement · score 0.16
  • platelet count · score 0.02
  • myeloid white cell count · score 0.02
  • ulcerative colitis · score 0.01
  • Alzheimer disease · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-C9JVW0-F1alphafoldPREDICTED59.47—

Amino-acid sequence (142 residues)

MRGTSCVGGG AESPGGAGLS EGPRGRWLRL APVCAYFLCV SLAAVLLAVY YGLIWVPTRS PAAPAGPQPS APSPPCAARP GVPPVPAPAA ASLSCLLGVP GGPRPQLQLP LSRRRRYSDP DRRPSRQTPR ETPEAAEGRR PG

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Quick facts

UniProtC9JVW0
GeneINAFM1
OrganismHomo sapiens
Length142
Binders0
Diseases13
View on UniProt