Multicilin (MCIDAS)

About Multicilin

Multicilin (MCIDAS) is a protein from Homo sapiens identified by UniProt accession D6RGH6, 385 residues long. MolForge cross-references it against 0 known binders and 39 disease associations.

Target properties

Protein name	Multicilin
UniProt accession	D6RGH6
Gene	MCIDAS
Organism	Homo sapiens
Length	385 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (39)

Diseases linked to this target (Open Targets).

primary ciliary dyskinesia · score 0.73
neurodegenerative disease · score 0.28
genetic disorder · score 0.19
eosinophil percentage of leukocytes · score 0.03
Merkel cell skin cancer · score 0.03
ring chromosome Y · score 0.03
eosinophil count · score 0.03
colorectal cancer · score 0.03
neoplasm · score 0.02
non-small cell lung carcinoma · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-D6RGH6-F1	alphafold	PREDICTED	60.62	—

Amino-acid sequence (385 residues)

MQACGGGAAG RRAFDSICPN RMLALPGRAL LCKPGKPERK FAPPRKFFPG CTGGSPVSVY EDPPDAEPTA LPALTTIDLQ DLADCSSLLG SDAPPGGDLA ASQNHSHQTE ADFNLQDFRD TVDDLISDSS SMMSPTLASG DFPFSPCDIS PFGPCLSPPL DPRALQSPPL RPPDVPPPEQ YWKEVADQNQ RALGDALVEN NQLHVTLTQK QEEIASLKER NVQLKELASR TRHLASVLDK LMITQSRDCG AAAEPFLLKA KAKRSLEELV SAAGQDCAEV DAILREISER CDEALQSRDP KRPRLLPEPA NTDTRPGNLH GAFRGLRTDC SRSALNLSHS ELEEGGSFST RIRSHSTIRT LAFPQGNAFT IRTANGGYKF RWVPS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards