Uroplakin-3b-like protein 2 (UPK3BL2)

About Uroplakin-3b-like protein 2

Uroplakin-3b-like protein 2 (UPK3BL2) is a protein from Homo sapiens identified by UniProt accession E5RIL1, 263 residues long. MolForge cross-references it against 0 known binders and 2 disease associations.

Target properties

Protein name	Uroplakin-3b-like protein 2
UniProt accession	E5RIL1
Gene	UPK3BL2
Organism	Homo sapiens
Length	263 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (2)

Diseases linked to this target (Open Targets).

diabetes mellitus · score 0.02
reticulocyte count · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-E5RIL1-F1	alphafold	PREDICTED	81.98	—

Amino-acid sequence (263 residues)

MDNSWRLGPA IGLSAGQSQL LVSLLLLLTR VQPGTDVAAP EHISYVPQLS NDTLAGRLTL STFTLEQPLG QFSSHNISDL DTIWLVVALS NATQSFTAPR TNQDIPAPAN FSQRGYYLTL RANRVLYQTR GQLHVLRVGN DTHCQPTKIG CNHPLPGPGP YRVKFLVMND EGPVAETKWS SDTRLQQAQA LRAVPGPQSP GTVVIIAILS ILLAVLLTVL LAVLIYTCFN SCRSTSLSGP EEAGSVRRYT THLAFSTPAE GAS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards