About Uncharacterized membrane protein C3orf80
Uncharacterized membrane protein C3orf80 (C3orf80) is a protein
from Homo sapiens identified by UniProt accession
F5H4A9, 247 residues long.
MolForge cross-references it against 0 known binders and
29 disease associations.
Target properties
| Protein name | Uncharacterized membrane protein C3orf80 |
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| UniProt accession | F5H4A9 |
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| Gene | C3orf80 |
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| Organism | Homo sapiens |
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| Length | 247 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (29)
Diseases linked to this target (Open Targets).
- monocyte count · score 0.38
- lymphocyte count · score 0.26
- PHF-tau measurement · score 0.23
- mean corpuscular volume · score 0.22
- neutrophil percentage of leukocytes · score 0.18
- spleen volume · score 0.05
- total cholesterol measurement · score 0.04
- platelet component distribution width · score 0.04
- eosinophil count · score 0.03
- glioblastoma multiforme · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-F5H4A9-F1 | alphafold | PREDICTED | 59.40 | — |
Amino-acid sequence (247 residues)
MWGPGVTAEG LSVAPAPPPL LPLLLLLALA LVAPSRGGGG CAELACGERE RCCDATNATA VRCCKLPLHA FLDNVGWFVR KLSGLLILLV LFAIGYFLQR IICPSPRRYP RGQARPGQRP GPPGGAGPLG GAGPPDDDDD SPALLRDEAA AGSQDSLLDS GGGGRGRGGG GRSDPSCASE HEMRVVSPVF LQLPSYEEVK YLPTYEESMR LQQLSPGEVV LPVSVLGRPR GGVAAEPDGG EGRYPLI
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