About Nuclear pore complex-interacting protein family member B12
Nuclear pore complex-interacting protein family member B12 (NPIPB12) is a protein
from Homo sapiens identified by UniProt accession
F8W0I5, 928 residues long.
MolForge cross-references it against 0 known binders and
0 disease associations.
Target properties
| Protein name | Nuclear pore complex-interacting protein family member B12 |
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| UniProt accession | F8W0I5 |
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| Gene | NPIPB12 |
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| Organism | Homo sapiens |
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| Length | 928 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-F8W0I5-F1 | alphafold | PREDICTED | 44.08 | — |
Amino-acid sequence (928 residues)
MVKLSIVLTP QFLSHDQGQL TKELQQHVKS VTCPCEYLRK VINTLADHHH RGTDFGGSPW LHVIIAFPTS YKVVITLWIV YLWVSLLKTI FWSRNGHDGS TDVQQRAWRS NRRRQEGLRS ICMHTKKRVS SFRGNKIGLK DVITLRRHVE TKVRAKIRKR KVTTKINHHD KINGKRKTAR KQKMFQRAQE LRRRAEDYHK CKIPPSARKA LCNWVRMAAA EHRHSSGLPY WPYLTAETLK NRMGHQPPPP TQQHSITDNS LSLKTPPECV LTPLPPSADD NLKTPPECVL TPLPPSADDN LKTPPECLLT PLPPSADDNL KTPPECLLTP LPPSADDNLK TPPECLLTPL PPSAPPSAPP SADDNLKTRA ECLLHPLPPS ADDNLKTPSE RQLTPLPPSA PPSADDNIKT PAERLRGPLP PSADDNLKTP SERQLTPLPP SAPPSADDNI KTPAFHPQRM IISRHLPSVS SLPFHPQLHS QQMIISRYLL SVCGFRFHHQ PMIISRHLPS VSSLPFHPQL HPQQMIISRH LPSVCGGRFH PQRMIISRHL PSVSSLPFHP QLHPQQMIIS RHLPSVCGGR FHPQRMIISR HLPSVSSLPF HPQLHPQQMI ISRHLPSVCG GRFHPQRMII SRHLPSVSSL PFHPQLHPQQ MIISRHLPSV CGERLRGPLP PSADDNLKTP SERQLTPLPP SAPPSADDNI KTPAERLRGP LPPSADDNLK TPSERQLTPL PPSAPPSADD NIKTPAERLR GPLPPSADDN LKTPSERQLT PLPPSAPPSA DDNIKTPAER LRGPLPPSAD DNLKTPPLAT QEAEAEKPRK PKRQRAAEME PPPEPKRRRV GDVEPSRKPK RRRAADVEPS SPEPKRRRVG DVEPSRKPKR RRAADVEPSS PEPKRRRVGD VEPSRKPKRR RAADVEPSLP EPKRRRLS
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