Coiled-coil domain-containing glutamate-rich…

About Coiled-coil domain-containing glutamate-rich protein 2

Coiled-coil domain-containing glutamate-rich protein 2 (CCER2) is a protein from Homo sapiens identified by UniProt accession I3L3R5, 266 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.

Target properties

Protein name	Coiled-coil domain-containing glutamate-rich protein 2
UniProt accession	I3L3R5
Gene	CCER2
Organism	Homo sapiens
Length	266 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (8)

Diseases linked to this target (Open Targets).

body height · score 0.14
hyperuricemia-pulmonary hypertension-renal failure-alkalosis syndrome · score 0.12
serum gamma-glutamyl transferase measurement · score 0.07
fat body mass · score 0.02
glioblastoma multiforme · score 0.02
psoriasis · score 0.02
Merkel cell skin cancer · score 0.01
Moyamoya disease · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-I3L3R5-F1	alphafold	PREDICTED	70.14	—

Amino-acid sequence (266 residues)

MPPRGPASEL LLLRLLLLGA ATAAPLAPRP SKEELTRCLA EVVTEVLTVG QVQRGPCTAL LHKELCGTEP HGCASTEEKG LLLGDFKKQE AGKMRSSQEV RDEEEEEVAE RTHKSEVQEQ AIRMQGHRQL HQEEDEEEEK EERKRGPMET FEDLWQRHLE NGGDLQKRVA EKASDKETAQ FQAEEKGVRV LGGDRSLWQG AERGGGERRE DLPHHHHHHH QPEAEPRQEK EEASEREEKE VEQLEHLRDE LKKVTETLGE QLRREG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Coiled-coil domain-containing glutamate-rich protein 2 (CCER2)