About Sulfotransferase 1C2
Sulfotransferase 1C2 (SULT1C2) is a protein
from Homo sapiens identified by UniProt accession
O00338, 296 residues long.
MolForge cross-references it against 0 known binders and
32 disease associations.
Target properties
| Protein name | Sulfotransferase 1C2 |
|---|
| UniProt accession | O00338 |
|---|
| Gene | SULT1C2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 296 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (32)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.41
- gut microbiome measurement · score 0.25
- malate measurement · score 0.24
- Agents acting on the renin-angiotensin system use measurement · score 0.11
- Barrett's esophagus · score 0.08
- esophageal adenocarcinoma · score 0.05
- hepatocellular carcinoma · score 0.05
- lobe attachment · score 0.03
- sessile serrated polyp · score 0.03
- gastric carcinoma · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O00338-F1 | alphafold | PREDICTED | 95.33 | — |
Amino-acid sequence (296 residues)
MALTSDLGKQ IKLKEVEGTL LQPATVDNWS QIQSFEAKPD DLLICTYPKA GTTWIQEIVD MIEQNGDVEK CQRAIIQHRH PFIEWARPPQ PSGVEKAKAM PSPRILKTHL STQLLPPSFW ENNCKFLYVA RNAKDCMVSY YHFQRMNHML PDPGTWEEYF ETFINGKVVW GSWFDHVKGW WEMKDRHQIL FLFYEDIKRD PKHEIRKVMQ FMGKKVDETV LDKIVQETSF EKMKENPMTN RSTVSKSILD QSISSFMRKG TVGDWKNHFT VAQNERFDEI YRRKMEGTSI NFCMEL
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