About Thioredoxin domain-containing protein 9
Thioredoxin domain-containing protein 9 (TXNDC9) is a protein
from Homo sapiens identified by UniProt accession
O14530, 226 residues long.
MolForge cross-references it against 0 known binders and
36 disease associations.
Target properties
| Protein name | Thioredoxin domain-containing protein 9 |
|---|
| UniProt accession | O14530 |
|---|
| Gene | TXNDC9 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 226 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (36)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- uterine fibroid · score 0.13
- Immature Reticulocyte Fraction Measurement · score 0.11
- body mass index · score 0.09
- mathematical ability · score 0.08
- hepatocellular carcinoma · score 0.08
- lifestyle measurement · score 0.07
- self reported educational attainment · score 0.06
- body fat percentage · score 0.06
- reticulocyte count · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O14530-F1 | alphafold | PREDICTED | 84.33 | — |
Amino-acid sequence (226 residues)
MEADASVDMF SKVLEHQLLQ TTKLVEEHLD SEIQKLDQMD EDELERLKEK RLQALRKAQQ QKQEWLSKGH GEYREIPSER DFFQEVKESE NVVCHFYRDS TFRCKILDRH LAILSKKHLE TKFLKLNVEK APFLCERLHI KVIPTLALLK DGKTQDYVVG FTDLGNTDDF TTETLEWRLG SSDILNYSGN LMEPPFQNQK KFGTNFTKLE KKTIRGKKYD SDSDDD
Explore Thioredoxin domain-containing protein 9 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets