Thymosin beta-4, Y-chromosomal (TMSB4Y)

About Thymosin beta-4, Y-chromosomal

Thymosin beta-4, Y-chromosomal (TMSB4Y) is a protein from Homo sapiens identified by UniProt accession O14604, 44 residues long. MolForge cross-references it against 0 known binders and 48 disease associations.

Target properties

Protein name	Thymosin beta-4, Y-chromosomal
UniProt accession	O14604
Gene	TMSB4Y
Organism	Homo sapiens
Length	44 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (48)

Diseases linked to this target (Open Targets).

breast carcinoma · score 0.05
factor VII deficiency · score 0.04
congenital factor X deficiency · score 0.04
Familial cerebral saccular aneurysm · score 0.04
left ventricular noncompaction · score 0.04
Congenital factor II deficiency · score 0.04
Congenital alpha2 antiplasmin deficiency · score 0.04
hemophilia A · score 0.04
aneurysm, intracranial berry, 12 · score 0.04
congenital factor V deficiency · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O14604-F1	alphafold	PREDICTED	79.92	—

Amino-acid sequence (44 residues)

MSDKPGMAEI EKFDKSKLKK TETQEKNPLS SKETIEQERQ AGES

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards