About Putative transcription factor Ovo-like 1
Putative transcription factor Ovo-like 1 (OVOL1) is a protein
from Homo sapiens identified by UniProt accession
O14753, 267 residues long.
MolForge cross-references it against 0 known binders and
255 disease associations.
Target properties
| Protein name | Putative transcription factor Ovo-like 1 |
|---|
| UniProt accession | O14753 |
|---|
| Gene | OVOL1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 267 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (255)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- sex hormone-binding globulin measurement · score 0.33
- atopic eczema · score 0.32
- asthma · score 0.32
- Eczematoid dermatitis · score 0.31
- urate measurement · score 0.30
- childhood onset asthma · score 0.29
- allergic disease · score 0.28
- age at onset · score 0.26
- allergic rhinitis · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O14753-F1 | alphafold | PREDICTED | 60.07 | — |
Amino-acid sequence (267 residues)
MPRAFLVKKP CVSTCKRNWS ELPDEERGEI YVPVSLGFCP PQPYREPEPS VAEPPSCPLA LNMSLRDSSY SMAPGPCVVA QLPSEDMGHL TDPQSRDHGF LRTKMKVTLG DSPSGDLFTC RVCQKAFTYQ RMLNRHMKCH NDVKRHLCTY CGKGFNDTFD LKRHVRTHTG VRPYKCSLCD KAFTQRCSLE SHLKKIHGVQ QKYAYKERRA KLYVCEECGC TSESQEGHVL HLKEHHPDSP LLRKTSKKVA VALQNTVTSL LQGSPHL
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