About Syntaxin-7
Syntaxin-7 (STX7) is a protein
from Homo sapiens identified by UniProt accession
O15400, 261 residues long.
MolForge cross-references it against 0 known binders and
37 disease associations.
Target properties
| Protein name | Syntaxin-7 |
|---|
| UniProt accession | O15400 |
|---|
| Gene | STX7 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 261 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (37)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.49
- reticulocyte count · score 0.46
- Red cell distribution width · score 0.43
- BMI-adjusted waist-hip ratio · score 0.38
- mean corpuscular hemoglobin concentration · score 0.37
- reticulocyte measurement · score 0.35
- waist-hip ratio · score 0.28
- BMI-adjusted waist circumference · score 0.28
- Abnormality of neuronal migration · score 0.26
- mean corpuscular volume · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O15400-F1 | alphafold | PREDICTED | 78.53 | — |
Amino-acid sequence (261 residues)
MSYTPGVGGD PAQLAQRISS NIQKITQCSV EIQRTLNQLG TPQDSPELRQ QLQQKQQYTN QLAKETDKYI KEFGSLPTTP SEQRQRKIQK DRLVAEFTTS LTNFQKVQRQ AAEREKEFVA RVRASSRVSG SFPEDSSKER NLVSWESQTQ PQVQVQDEEI TEDDLRLIHE RESSIRQLEA DIMDINEIFK DLGMMIHEQG DVIDSIEANV ENAEVHVQQA NQQLSRAADY QRKSRKTLCI IILILVIGVA IISLIIWGLN H
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