LYR motif-containing protein 1 (LYRM1)

About LYR motif-containing protein 1

LYR motif-containing protein 1 (LYRM1) is a protein from Homo sapiens identified by UniProt accession O43325, 122 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.

Target properties

Protein name	LYR motif-containing protein 1
UniProt accession	O43325
Gene	LYRM1
Organism	Homo sapiens
Length	122 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (31)

Diseases linked to this target (Open Targets).

eosinophil count · score 0.24
eosinophil percentage of leukocytes · score 0.14
mean corpuscular volume · score 0.13
body height · score 0.10
urate measurement · score 0.10
erythrocyte count · score 0.10
diastolic blood pressure · score 0.07
platelet count · score 0.06
platelet crit · score 0.06
sitting height measurement · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O43325-F1	alphafold	PREDICTED	85.60	—

Amino-acid sequence (122 residues)

MTTATRQEVL GLYRSIFRLA RKWQATSGQM EDTIKEKQYI LNEARTLFRK NKNLTDTDLI KQCIDECTAR IEIGLHYKIP YPRPIHLPPM GLTPLRGRGL RSQEKLRKLS KPVYLRSHDE VS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards