About Protein Mis18-beta
Protein Mis18-beta (OIP5) is a protein
from Homo sapiens identified by UniProt accession
O43482, 229 residues long.
MolForge cross-references it against 0 known binders and
205 disease associations.
Target properties
| Protein name | Protein Mis18-beta |
|---|
| UniProt accession | O43482 |
|---|
| Gene | OIP5 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 229 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (205)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.55
- neoplasm · score 0.11
- mean platelet volume · score 0.11
- hepatocellular carcinoma · score 0.10
- gonorrhea · score 0.10
- calf circumference measurement · score 0.10
- cancer · score 0.10
- non-small cell lung carcinoma · score 0.09
- nonpapillary renal cell carcinoma · score 0.09
- lung adenocarcinoma · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O43482-F1 | alphafold | PREDICTED | 75.27 | — |
Amino-acid sequence (229 residues)
MAAQPLRHRS RCATPPRGDF CGGTERAIDQ ASFTTSMEWD TQVVKGSSPL GPAGLGAEEP AAGPQLPSWL QPERCAVFQC AQCHAVLADS VHLAWDLSRS LGAVVFSRVT NNVVLEAPFL VGIEGSLKGS TYNLLFCGSC GIPVGFHLYS THAALAALRG HFCLSSDKMV CYLLKTKAIV NASEMDIQNV PLSEKIAELK EKIVLTHNRL KSLMKILSEV TPDQSKPEN
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