About Protein sprouty homolog 3
Protein sprouty homolog 3 (SPRY3) is a protein
from Homo sapiens identified by UniProt accession
O43610, 288 residues long.
MolForge cross-references it against 0 known binders and
31 disease associations.
Target properties
| Protein name | Protein sprouty homolog 3 |
|---|
| UniProt accession | O43610 |
|---|
| Gene | SPRY3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 288 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (31)
Diseases linked to this target (Open Targets).
- hemoglobin measurement · score 0.20
- Red cell distribution width · score 0.20
- erythrocyte count · score 0.20
- mean corpuscular volume · score 0.20
- hematocrit · score 0.20
- mean corpuscular hemoglobin · score 0.20
- triglyceride measurement · score 0.09
- total cholesterol measurement · score 0.09
- low density lipoprotein cholesterol measurement · score 0.09
- body mass index · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O43610-F1 | alphafold | PREDICTED | 63.19 | — |
Amino-acid sequence (288 residues)
MDAAVTDDFQ QILPIEQLRS THASNDYVER PPAPCKQALS SPSLIVQTHK SDWSLATMPT SLPRSLSQCH QLQPLPQHLS QSSIASSMSH STTASDQRLL ASITPSPSGQ SIIRTQPGAG VHPKADGALK GEAEQSAGHP SEHLFICEEC GRCKCVPCTA ARPLPSCWLC NQRCLCSAES LLDYGTCLCC VKGLFYHCST DDEDNCADEP CSCGPSSCFV RWAAMSLISL FLPCLCCYLP TRGCLHLCQQ GYDSLRRPGC RCKRHTNTVC RKISSGSAPF PKAQEKSV
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