About Sulfotransferase 1B1
Sulfotransferase 1B1 (SULT1B1) is a protein
from Homo sapiens identified by UniProt accession
O43704, 296 residues long.
MolForge cross-references it against 0 known binders and
34 disease associations.
Target properties
| Protein name | Sulfotransferase 1B1 |
|---|
| UniProt accession | O43704 |
|---|
| Gene | SULT1B1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 296 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (34)
Diseases linked to this target (Open Targets).
- uterine fibroid · score 0.47
- Uterine leiomyoma · score 0.25
- neuroinflammatory disorder · score 0.23
- glioblastoma multiforme · score 0.16
- heel bone mineral density · score 0.11
- Barrett's esophagus · score 0.05
- C-X-C motif chemokine 10 measurement · score 0.03
- sex hormone-binding globulin measurement · score 0.03
- pulse pressure measurement · score 0.02
- colorectal adenocarcinoma · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O43704-F1 | alphafold | PREDICTED | 97.78 | — |
Amino-acid sequence (296 residues)
MLSPKDILRK DLKLVHGYPM TCAFASNWEK IEQFHSRPDD IVIATYPKSG TTWVSEIIDM ILNDGDIEKC KRGFITEKVP MLEMTLPGLR TSGIEQLEKN PSPRIVKTHL PTDLLPKSFW ENNCKMIYLA RNAKDVSVSY YHFDLMNNLQ PFPGTWEEYL EKFLTGKVAY GSWFTHVKNW WKKKEEHPIL FLYYEDMKEN PKEEIKKIIR FLEKNLNDEI LDRIIHHTSF EVMKDNPLVN YTHLPTTVMD HSKSPFMRKG TAGDWKNYFT VAQNEKFDAI YETEMSKTAL QFRTEI
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