About Synaptogyrin-2
Synaptogyrin-2 (SYNGR2) is a protein
from Homo sapiens identified by UniProt accession
O43760, 224 residues long.
MolForge cross-references it against 0 known binders and
46 disease associations.
Target properties
| Protein name | Synaptogyrin-2 |
|---|
| UniProt accession | O43760 |
|---|
| Gene | SYNGR2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 224 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (46)
Diseases linked to this target (Open Targets).
- body height · score 0.29
- red blood cell density measurement · score 0.22
- drug use measurement · score 0.14
- erythrocyte count · score 0.11
- neoplasm · score 0.08
- cancer · score 0.07
- Red cell distribution width · score 0.07
- MODY · score 0.05
- reticulocyte count · score 0.04
- diabetes mellitus, permanent neonatal 4 · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O43760-F1 | alphafold | PREDICTED | 80.97 | — |
Amino-acid sequence (224 residues)
MESGAYGAAK AGGSFDLRRF LTQPQVVARA VCLVFALIVF SCIYGEGYSN AHESKQMYCV FNRNEDACRY GSAIGVLAFL ASAFFLVVDA YFPQISNATD RKYLVIGDLL FSALWTFLWF VGFCFLTNQW AVTNPKDVLV GADSVRAAIT FSFFSIFSWG VLASLAYQRY KAGVDDFIQN YVDPTPDPNT AYASYPGASV DNYQQPPFTQ NAETTEGYQP PPVY
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