About Synaptogyrin-3
Synaptogyrin-3 (SYNGR3) is a protein
from Homo sapiens identified by UniProt accession
O43761, 229 residues long.
MolForge cross-references it against 0 known binders and
42 disease associations.
Target properties
| Protein name | Synaptogyrin-3 |
|---|
| UniProt accession | O43761 |
|---|
| Gene | SYNGR3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 229 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (42)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.16
- neoplasm · score 0.07
- mean platelet volume · score 0.04
- glioblastoma multiforme · score 0.04
- atypical teratoid rhabdoid tumor · score 0.04
- astrocytoma · score 0.04
- ependymoma · score 0.03
- central nervous system cancer · score 0.03
- chromophobe renal cell carcinoma · score 0.02
- oligodendroglioma · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O43761-F1 | alphafold | PREDICTED | 80.30 | — |
Amino-acid sequence (229 residues)
MEGASFGAGR AGAALDPVSF ARRPQTLLRV ASWVFSIAVF GPIVNEGYVN TDSGPELRCV FNGNAGACRF GVALGLGAFL ACAAFLLLDV RFQQISSVRD RRRAVLLDLG FSGLWSFLWF VGFCFLTNQW QRTAPGPATT QAGDAARAAI AFSFFSILSW VALTVKALQR FRLGTDMSLF ATEQLSTGAS QAYPGYPVGS GVEGTETYQS PPFTETLDTS PKGYQVPAY
Explore Synaptogyrin-3 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets