Protein SSX4 (SSX4)

About Protein SSX4

Protein SSX4 (SSX4) is a protein from Homo sapiens identified by UniProt accession O60224, 188 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.

Target properties

Protein name	Protein SSX4
UniProt accession	O60224
Gene	SSX4
Organism	Homo sapiens
Length	188 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (5)

Diseases linked to this target (Open Targets).

acute myeloid leukemia · score 0.37
squamous cell lung carcinoma · score 0.28
thyroid carcinoma · score 0.28
hepatocellular carcinoma · score 0.18
breast ductal carcinoma in situ · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O60224-F1	alphafold	PREDICTED	68.39	—

Amino-acid sequence (188 residues)

MNGDDAFARR PRDDAQISEK LRKAFDDIAK YFSKKEWEKM KSSEKIVYVY MKLNYEVMTK LGFKVTLPPF MRSKRAADFH GNDFGNDRNH RNQVERPQMT FGSLQRIFPK IMPKKPAEEE NGLKEVPEAS GPQNDGKQLC PPGNPSTLEK INKTSGPKRG KHAWTHRLRE RKQLVVYEEI SDPEEDDE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards