Glia maturation factor gamma (GMFG)

About Glia maturation factor gamma

Glia maturation factor gamma (GMFG) is a protein from Homo sapiens identified by UniProt accession O60234, 142 residues long. MolForge cross-references it against 0 known binders and 74 disease associations.

Target properties

Protein name	Glia maturation factor gamma
UniProt accession	O60234
Gene	GMFG
Organism	Homo sapiens
Length	142 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (74)

Diseases linked to this target (Open Targets).

inflammatory bowel disease · score 0.14
breast cancer · score 0.09
cancer · score 0.08
triple-negative breast cancer · score 0.08
drug use measurement · score 0.07
IGA glomerulonephritis · score 0.07
neoplasm · score 0.06
glioblastoma multiforme · score 0.05
isolated hyperchlorhidrosis · score 0.03
non-small cell lung carcinoma · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O60234-F1	alphafold	PREDICTED	94.18	—

Amino-acid sequence (142 residues)

MSDSLVVCEV DPELTEKLRK FRFRKETDNA AIIMKVDKDR QMVVLEEEFQ NISPEELKME LPERQPRFVV YSYKYVHDDG RVSYPLCFIF SSPVGCKPEQ QMMYAGSKNR LVQTAELTKV FEIRTTDDLT EAWLQEKLSF FR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards