About Sushi domain-containing protein 5
Sushi domain-containing protein 5 (SUSD5) is a protein
from Homo sapiens identified by UniProt accession
O60279, 629 residues long.
MolForge cross-references it against 0 known binders and
28 disease associations.
Target properties
| Protein name | Sushi domain-containing protein 5 |
|---|
| UniProt accession | O60279 |
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| Gene | SUSD5 |
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| Organism | Homo sapiens |
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| Length | 629 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (28)
Diseases linked to this target (Open Targets).
- vital capacity · score 0.42
- neurodegenerative disease · score 0.41
- body height · score 0.40
- appendicular lean mass · score 0.36
- forced expiratory volume · score 0.31
- IGF-1 measurement · score 0.30
- total blood protein measurement · score 0.29
- sitting height measurement · score 0.26
- Abnormality of refraction · score 0.25
- BMI-adjusted hip circumference · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O60279-F1 | alphafold | PREDICTED | 56.07 | — |
Amino-acid sequence (629 residues)
MTAEGPSPPA RWHRRLPGLW AAALLLLGLP RLSVRADGKF FVLESQNGSQ GLQLEAARLS CKSRGAHLAS ADELRRVVQD CSFAVCTTGW LADGTLGTTV CSKGSGEQQI MRAVDVRIES NPVPGGTYSA LCIKDEEKPC GDPPSFPHTI LQGRTGLEMG DELLYVCAPG HIMGHRETAF TLLCNSCGEW YGLVQACGKD EAEAHIDYED NFPDDRSVSF RELMEDSRTE ADEDRGQGDS SEEAPKQDRL VSISVGRENI ARDKVFVPTT GLPGAGSSVP ADSPGSRLLQ KHLFWFPAEA FHKPGLEKEV DDDTKKQFSA GDNHSGVKLV PGEPETKVIY GNTDGPSGPF VGKNDSKAGD PVVSSSDESW LDGYPVTEGA WRKTEAEEEE DGDRGDGSVG LDENVLVTPD QPILVEVKKP KSSTLTPSEG MTHSSVLPSQ MLDVEALALR PVNASETEGI GDGDLTKYQS TLPWRFITEE SPMATLSYEL TSSTLEILTV NTVKQTPNHI PSTIMATTQP PVETTVPEIQ DSFPYLLSED FFGQEGPGPG ASEELHPTLE SCVGDGCPGL SRGPVIATIV TVLCLLLLLA GVGMVWGYRK CQHKSSVYKL NVGQRQARHY HQQIEMEKV
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