About Syntaxin-10
Syntaxin-10 (STX10) is a protein
from Homo sapiens identified by UniProt accession
O60499, 249 residues long.
MolForge cross-references it against 0 known binders and
21 disease associations.
Target properties
| Protein name | Syntaxin-10 |
|---|
| UniProt accession | O60499 |
|---|
| Gene | STX10 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 249 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (21)
Diseases linked to this target (Open Targets).
- venous thromboembolism · score 0.18
- sex hormone-binding globulin measurement · score 0.11
- age at first birth measurement · score 0.08
- body height · score 0.08
- self reported educational attainment · score 0.07
- brain volume measurement · score 0.06
- mathematical ability · score 0.06
- infection · score 0.06
- infect · score 0.06
- appendicular lean mass · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O60499-F1 | alphafold | PREDICTED | 80.46 | — |
Amino-acid sequence (249 residues)
MSLEDPFFVV RGEVQKAVNT ARGLYQRWCE LLQESAAVGR EELDWTTNEL RNGLRSIEWD LEDLEETIGI VEANPGKFKL PAGDLQERKV FVERMREAVQ EMKDHMVSPT AVAFLERNNR EILAGKPAAQ KSPSDLLDAS AVSATSRYIE EQQATQQLIM DEQDQQLEMV SGSIQVLKHM SGRVGEELDE QGIMLDAFAQ EMDHTQSRMD GVLRKLAKVS HMTSDRRQWC AIAVLVGVLL LVLILLFSL
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