About TIP41-like protein
TIP41-like protein (TIPRL) is a protein
from Homo sapiens identified by UniProt accession
O75663, 272 residues long.
MolForge cross-references it against 0 known binders and
43 disease associations.
Target properties
| Protein name | TIP41-like protein |
|---|
| UniProt accession | O75663 |
|---|
| Gene | TIPRL |
|---|
| Organism | Homo sapiens |
|---|
| Length | 272 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (43)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.42
- Red cell distribution width · score 0.27
- mean corpuscular volume · score 0.25
- leukocyte count · score 0.23
- hemoglobin A1 measurement · score 0.18
- HbA1c measurement · score 0.17
- protein measurement · score 0.16
- hepatocellular carcinoma · score 0.10
- non-small cell lung carcinoma · score 0.08
- neoplasm · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O75663-F1 | alphafold | PREDICTED | 84.80 | — |
Amino-acid sequence (272 residues)
MMIHGFQSSH RDFCFGPWKL TASKTHIMKS ADVEKLADEL HMPSLPEMMF GDNVLRIQHG SGFGIEFNAT DALRCVNNYQ GMLKVACAEE WQESRTEGEH SKEVIKPYDW TYTTDYKGTL LGESLKLKVV PTTDHIDTEK LKAREQIKFF EEVLLFEDEL HDHGVSSLSV KIRVMPSSFF LLLRFFLRID GVLIRMNDTR LYHEADKTYM LREYTSRESK ISSLMHVPPS LFTEPNEISQ YLPIKEAVCE KLIFPERIDP NPADSQKSTQ VE
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