About Tumor necrosis factor ligand superfamily member 13
Tumor necrosis factor ligand superfamily member 13 (TNFSF13) is a protein
from Homo sapiens identified by UniProt accession
O75888, 250 residues long.
MolForge cross-references it against 0 known binders and
398 disease associations.
Target properties
| Protein name | Tumor necrosis factor ligand superfamily member 13 |
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| UniProt accession | O75888 |
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| Gene | TNFSF13 |
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| Organism | Homo sapiens |
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| Length | 250 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Approved drugs hitting this target (1)
DrugCentral-linked approved drugs that act on this protein.
Disease associations (398)
Diseases linked to this target (Open Targets).
- total blood protein measurement · score 0.52
- sex hormone-binding globulin measurement · score 0.37
- IGA glomerulonephritis · score 0.35
- serum non-albumin protein measurement · score 0.29
- lupus nephritis · score 0.29
- blood protein measurement · score 0.28
- high density lipoprotein cholesterol measurement · score 0.27
- alcohol consumption measurement · score 0.27
- serum albumin measurement · score 0.23
- albumin:globulin ratio measurement · score 0.22
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O75888-F1 | alphafold | PREDICTED | 81.16 | — |
Amino-acid sequence (250 residues)
MPASSPFLLA PKGPPGNMGG PVREPALSVA LWLSWGAALG AVACAMALLT QQTELQSLRR EVSRLQGTGG PSQNGEGYPW QSLPEQSSDA LEAWENGERS RKRRAVLTQK QKKQHSVLHL VPINATSKDD SDVTEVMWQP ALRRGRGLQA QGYGVRIQDA GVYLLYSQVL FQDVTFTMGQ VVSREGQGRQ ETLFRCIRSM PSHPDRAYNS CYSAGVFHLH QGDILSVIIP RARAKLNLSP HGTFLGFVKL
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