Sulfotransferase 1C4 (SULT1C4)

About Sulfotransferase 1C4

Sulfotransferase 1C4 (SULT1C4) is a protein from Homo sapiens identified by UniProt accession O75897, 302 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.

Target properties

Protein name	Sulfotransferase 1C4
UniProt accession	O75897
Gene	SULT1C4
Organism	Homo sapiens
Length	302 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (19)

Diseases linked to this target (Open Targets).

gut microbiome measurement · score 0.11
low density lipoprotein cholesterol measurement · score 0.09
lobe attachment · score 0.08
facial hair thickness measurement · score 0.07
helix rolling · score 0.04
hypouricemia, renal, 2 · score 0.03
hypermetabolism due to uncoupled mitochondrial oxidative phosphorylation 2 · score 0.03
Down syndrome · score 0.03
platelet count · score 0.02
lung adenocarcinoma · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O75897-F1	alphafold	PREDICTED	94.71	—

Amino-acid sequence (302 residues)

MALHDMEDFT FDGTKRLSVN YVKGILQPTD TCDIWDKIWN FQAKPDDLLI STYPKAGTTW TQEIVELIQN EGDVEKSKRA PTHQRFPFLE MKIPSLGSGL EQAHAMPSPR ILKTHLPFHL LPPSLLEKNC KIIYVARNPK DNMVSYYHFQ RMNKALPAPG TWEEYFETFL AGKVCWGSWH EHVKGWWEAK DKHRILYLFY EDMKKNPKHE IQKLAEFIGK KLDDKVLDKI VHYTSFDVMK QNPMANYSSI PAEIMDHSIS PFMRKGAVGD WKKHFTVAQN ERFDEDYKKK MTDTRLTFHF QF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards