About Stanniocalcin-2
Stanniocalcin-2 (STC2) is a protein
from Homo sapiens identified by UniProt accession
O76061, 302 residues long.
MolForge cross-references it against 0 known binders and
197 disease associations.
Target properties
| Protein name | Stanniocalcin-2 |
|---|
| UniProt accession | O76061 |
|---|
| Gene | STC2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 302 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (197)
Diseases linked to this target (Open Targets).
- lean body mass · score 0.70
- body height · score 0.65
- sitting height measurement · score 0.61
- anthropometric measurement · score 0.55
- whole body water mass · score 0.54
- base metabolic rate measurement · score 0.53
- forced expiratory volume · score 0.48
- BMI-adjusted waist-hip ratio · score 0.47
- appendicular lean mass · score 0.46
- body weights and measures · score 0.45
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O76061-F1 | alphafold | PREDICTED | 73.03 | — |
Amino-acid sequence (302 residues)
MCAERLGQFM TLALVLATFD PARGTDATNP PEGPQDRSSQ QKGRLSLQNT AEIQHCLVNA GDVGCGVFEC FENNSCEIRG LHGICMTFLH NAGKFDAQGK SFIKDALKCK AHALRHRFGC ISRKCPAIRE MVSQLQRECY LKHDLCAAAQ ENTRVIVEMI HFKDLLLHEP YVDLVNLLLT CGEEVKEAIT HSVQVQCEQN WGSLCSILSF CTSAIQKPPT APPERQPQVD RTKLSRAHHG EAGHHLPEPS SRETGRGAKG ERGSKSHPNA HARGRVGGLG AQGPSGSSEW EDEQSEYSDI RR
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