Lymphocyte antigen 6H (LY6H)

About Lymphocyte antigen 6H

Lymphocyte antigen 6H (LY6H) is a protein from Homo sapiens identified by UniProt accession O94772, 140 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.

Target properties

Protein name	Lymphocyte antigen 6H
UniProt accession	O94772
Gene	LY6H
Organism	Homo sapiens
Length	140 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (28)

Diseases linked to this target (Open Targets).

mathematical ability · score 0.28
diet measurement · score 0.25
smoking status measurement · score 0.18
health study participation · score 0.17
high density lipoprotein cholesterol measurement · score 0.07
glioblastoma multiforme · score 0.03
cancer · score 0.02
astrocytoma · score 0.02
oligodendroglioma · score 0.02
large cell medulloblastoma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O94772-F1	alphafold	PREDICTED	75.82	—

Amino-acid sequence (140 residues)

MLPAAMKGLG LALLAVLLCS APAHGLWCQD CTLTTNSSHC TPKQCQPSDT VCASVRITDP SSSRKDHSVN KMCASSCDFV KRHFFSDYLM GFINSGILKV DVDCCEKDLC NGAAGAGHSP WALAGGLLLS LGPALLWAGP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards