STAGA complex 65 subunit gamma (SUPT7L)

About STAGA complex 65 subunit gamma

STAGA complex 65 subunit gamma (SUPT7L) is a protein from Homo sapiens identified by UniProt accession O94864, 414 residues long. MolForge cross-references it against 0 known binders and 79 disease associations.

Target properties

Protein name	STAGA complex 65 subunit gamma
UniProt accession	O94864
Gene	SUPT7L
Organism	Homo sapiens
Length	414 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (79)

Diseases linked to this target (Open Targets).

breast adenocarcinoma · score 0.22
hemoglobin measurement · score 0.17
systolic blood pressure · score 0.11
erythrocyte count · score 0.08
uncombable hair syndrome · score 0.07
very low density lipoprotein cholesterol measurement · score 0.06
chylomicron measurement · score 0.06
phospholipid measurement · score 0.06
alcohol consumption measurement · score 0.05
Woolly hair · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O94864-F1	alphafold	PREDICTED	64.96	—

Amino-acid sequence (414 residues)

MNLQRYWGEI PISSSQTNRS SFDLLPREFR LVEVHDPPLH QPSANKPKPP TMLDIPSEPC SLTIHTIQLI QHNRRLRNLI ATAQAQNQQQ TEGVKTEESE PLPSCPGSPP LPDDLLPLDC KNPNAPFQIR HSDPESDFYR GKGEPVTELS WHSCRQLLYQ AVATILAHAG FDCANESVLE TLTDVAHEYC LKFTKLLRFA VDREARLGQT PFPDVMEQVF HEVGIGSVLS LQKFWQHRIK DYHSYMLQIS KQLSEEYERI VNPEKATEDA KPVKIKEEPV SDITFPVSEE LEADLASGDQ SLPMGVLGAQ SERFPSNLEV EASPQASSAE VNASPLWNLA HVKMEPQESE EGNVSGHGVL GSDVFEEPMS GMSEAGIPQS PDDSDSSYGS HSTDSLMGSS PVFNQRCKKR MRKI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards