Luc7-like protein 3 (LUC7L3)

About Luc7-like protein 3

Luc7-like protein 3 (LUC7L3) is a protein from Homo sapiens identified by UniProt accession O95232, 432 residues long. MolForge cross-references it against 0 known binders and 53 disease associations.

Target properties

Protein name	Luc7-like protein 3
UniProt accession	O95232
Gene	LUC7L3
Organism	Homo sapiens
Length	432 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (53)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.48
urate measurement · score 0.15
bone density · score 0.15
hepatocellular carcinoma · score 0.05
primary familial polycythemia due to EPO receptor mutation · score 0.05
heel bone mineral density · score 0.05
hemolytic anemia due to diphosphoglycerate mutase deficiency · score 0.04
dehydrated hereditary stomatocytosis · score 0.04
Pyruvate kinase hyperactivity · score 0.04
hemolytic anemia due to erythrocyte adenosine deaminase overproduction · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O95232-F1	alphafold	PREDICTED	70.18	—

Amino-acid sequence (432 residues)

MISAAQLLDE LMGRDRNLAP DEKRSNVRWD HESVCKYYLC GFCPAELFTN TRSDLGPCEK IHDENLRKQY EKSSRFMKVG YERDFLRYLQ SLLAEVERRI RRGHARLALS QNQQSSGAAG PTGKNEEKIQ VLTDKIDVLL QQIEELGSEG KVEEAQGMMK LVEQLKEERE LLRSTTSTIE SFAAQEKQME VCEVCGAFLI VGDAQSRVDD HLMGKQHMGY AKIKATVEEL KEKLRKRTEE PDRDERLKKE KQEREEREKE REREREERER KRRREEEERE KERARDRERR KRSRSRSRHS SRTSDRRCSR SRDHKRSRSR ERRRSRSRDR RRSRSHDRSE RKHRSRSRDR RRSKSRDRKS YKHRSKSRDR EQDRKSKEKE KRGSDDKKSS VKSGSREKQS EDTNTESKES DTKNEVNGTS EDIKSEGDTQ SN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards