About Tumor necrosis factor alpha-induced protein 8
Tumor necrosis factor alpha-induced protein 8 (TNFAIP8) is a protein
from Homo sapiens identified by UniProt accession
O95379, 198 residues long.
MolForge cross-references it against 0 known binders and
180 disease associations.
Target properties
| Protein name | Tumor necrosis factor alpha-induced protein 8 |
|---|
| UniProt accession | O95379 |
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| Gene | TNFAIP8 |
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| Organism | Homo sapiens |
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| Length | 198 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (180)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.51
- neurodegenerative disease · score 0.50
- asthma · score 0.48
- BMI-adjusted waist-hip ratio · score 0.48
- neutrophil count · score 0.45
- triglyceride measurement · score 0.43
- Eczematoid dermatitis · score 0.43
- myeloid white cell count · score 0.43
- high density lipoprotein cholesterol measurement · score 0.43
- vital capacity · score 0.43
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95379-F1 | alphafold | PREDICTED | 89.29 | — |
Amino-acid sequence (198 residues)
MHSEAEESKE VATDVFNSKN LAVQAQKKIL GKMVSKSIAT TLIDDTSSEV LDELYRVTRE YTQNKKEAEK IIKNLIKTVI KLAILYRNNQ FNQDELALME KFKKKVHQLA MTVVSFHQVD YTFDRNVLSR LLNECREMLH QIIQRHLTAK SHGRVNNVFD HFSDCEFLAA LYNPFGNFKP HLQKLCDGIN KMLDEENI
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