Synaptogyrin-4 (SYNGR4)

About Synaptogyrin-4

Synaptogyrin-4 (SYNGR4) is a protein from Homo sapiens identified by UniProt accession O95473, 234 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.

Target properties

Protein name	Synaptogyrin-4
UniProt accession	O95473
Gene	SYNGR4
Organism	Homo sapiens
Length	234 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (7)

Diseases linked to this target (Open Targets).

non-small cell lung carcinoma · score 0.03
axial length measurement · score 0.02
Amyotrophic lateral sclerosis · score 0.01
nervous system disease · score 0.01
neoplasm · score 0.01
cancer · score 0.01
chronic kidney disease · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O95473-F1	alphafold	PREDICTED	77.18	—

Amino-acid sequence (234 residues)

MHIPKSLQEL ANSEAVQFLR RPKTITRVFE GVFSLIVFSS LLTDGYQNKM ESPQLHCILN SNSVACSFAV GAGFLAFLSC LAFLVLDTQE TRIAGTRFKT AFQLLDFILA VLWAVVWFMG FCFLANQWQH SPPKEFLLGS SSAQAAIAFT FFSILVWIFQ AYLAFQDLRN DAPVPYKRFL DEGGMVLTTL PLPSANSPVN MPTTGPNSLS YASSALSPCL TAPKSPRLAM MPDN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards