About Solute carrier family 2, facilitated glucose transporter member 10
Solute carrier family 2, facilitated glucose transporter member 10 (SLC2A10) is a protein
from Homo sapiens identified by UniProt accession
O95528, 541 residues long.
MolForge cross-references it against 0 known binders and
98 disease associations.
Target properties
| Protein name | Solute carrier family 2, facilitated glucose transporter member 10 |
|---|
| UniProt accession | O95528 |
|---|
| Gene | SLC2A10 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 541 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (98)
Diseases linked to this target (Open Targets).
- arterial tortuosity syndrome · score 0.83
- familial thoracic aortic aneurysm and aortic dissection · score 0.55
- Rare disease with thoracic aortic aneurysm and aortic dissection · score 0.54
- Abnormality of the cardiovascular system · score 0.45
- Prolonged QT interval · score 0.34
- familial lipoprotein lipase deficiency · score 0.34
- Familial hemophagocytic lymphohistiocytosis · score 0.27
- heel bone mineral density · score 0.16
- facial morphology measurement · score 0.16
- aortic aneurysm, familial thoracic 6 · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95528-F1 | alphafold | PREDICTED | 74.72 | — |
Amino-acid sequence (541 residues)
MGHSPPVLPL CASVSLLGGL TFGYELAVIS GALLPLQLDF GLSCLEQEFL VGSLLLGALL ASLVGGFLID CYGRKQAILG SNLVLLAGSL TLGLAGSLAW LVLGRAVVGF AISLSSMACC IYVSELVGPR QRGVLVSLYE AGITVGILLS YALNYALAGT PWGWRHMFGW ATAPAVLQSL SLLFLPAGTD ETATHKDLIP LQGGEAPKLG PGRPRYSFLD LFRARDNMRG RTTVGLGLVL FQQLTGQPNV LCYASTIFSS VGFHGGSSAV LASVGLGAVK VAATLTAMGL VDRAGRRALL LAGCALMALS VSGIGLVSFA VPMDSGPSCL AVPNATGQTG LPGDSGLLQD SSLPPIPRTN EDQREPILST AKKTKPHPRS GDPSAPPRLA LSSALPGPPL PARGHALLRW TALLCLMVFV SAFSFGFGPV TWLVLSEIYP VEIRGRAFAF CNSFNWAANL FISLSFLDLI GTIGLSWTFL LYGLTAVLGL GFIYLFVPET KGQSLAEIDQ QFQKRRFTLS FGHRQNSTGI PYSRIEISAA S
Explore Solute carrier family 2, facilitated glucose transporter member 10 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets