About YEATS domain-containing protein 4
YEATS domain-containing protein 4 (YEATS4) is a protein
from Homo sapiens identified by UniProt accession
O95619, 227 residues long.
MolForge cross-references it against 0 known binders and
84 disease associations.
Target properties
| Protein name | YEATS domain-containing protein 4 |
|---|
| UniProt accession | O95619 |
|---|
| Gene | YEATS4 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 227 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (84)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- triglyceride measurement · score 0.32
- lymphocyte percentage of leukocytes · score 0.27
- neutrophil count · score 0.25
- breast adenocarcinoma · score 0.23
- C-reactive protein measurement · score 0.23
- myeloid white cell count · score 0.23
- body mass index · score 0.23
- Uterine leiomyoma · score 0.22
- creatinine measurement · score 0.22
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95619-F1 | alphafold | PREDICTED | 91.55 | — |
Amino-acid sequence (227 residues)
MFKRMAEFGP DSGGRVKGVT IVKPIVYGNV ARYFGKKREE DGHTHQWTVY VKPYRNEDMS AYVKKIQFKL HESYGNPLRV VTKPPYEITE TGWGEFEIII KIFFIDPNER PVTLYHLLKL FQSDTNAMLG KKTVVSEFYD EMIFQDPTAM MQQLLTTSRQ LTLGAYKHET EFAELEVKTR EKLEAAKKKT SFEIAELKER LKASRETINC LKNEIRKLEE DDQAKDI
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