About Transmembrane protein 50A
Transmembrane protein 50A (TMEM50A) is a protein
from Homo sapiens identified by UniProt accession
O95807, 157 residues long.
MolForge cross-references it against 0 known binders and
41 disease associations.
Target properties
| Protein name | Transmembrane protein 50A |
|---|
| UniProt accession | O95807 |
|---|
| Gene | TMEM50A |
|---|
| Organism | Homo sapiens |
|---|
| Length | 157 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (41)
Diseases linked to this target (Open Targets).
- mean corpuscular hemoglobin concentration · score 0.41
- reticulocyte count · score 0.35
- mean corpuscular volume · score 0.32
- mean reticulocyte volume · score 0.30
- platelet count · score 0.26
- reticulocyte measurement · score 0.17
- Red cell distribution width · score 0.16
- bilirubin measurement · score 0.15
- blood protein measurement · score 0.15
- serum albumin measurement · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95807-F1 | alphafold | PREDICTED | 83.26 | — |
Amino-acid sequence (157 residues)
MSGFLEGLRC SECIDWGEKR NTIASIAAGV LFFTGWWIII DAAVIYPTMK DFNHSYHACG VIATIAFLMI NAVSNGQVRG DSYSEGCLGQ TGARIWLFVG FMLAFGSLIA SMWILFGGYV AKEKDIVYPG IAVFFQNAFI FFGGLVFKFG RTEDLWQ
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