About Chloride intracellular channel protein 3
Chloride intracellular channel protein 3 (CLIC3) is a protein
from Homo sapiens identified by UniProt accession
O95833, 236 residues long.
MolForge cross-references it against 0 known binders and
69 disease associations.
Target properties
| Protein name | Chloride intracellular channel protein 3 |
|---|
| UniProt accession | O95833 |
|---|
| Gene | CLIC3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 236 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (69)
Diseases linked to this target (Open Targets).
- puerperal disorder · score 0.09
- cancer · score 0.09
- urinary bladder carcinoma · score 0.08
- breast cancer · score 0.08
- blood protein measurement · score 0.07
- lymphocyte percentage of leukocytes · score 0.06
- schizophrenia · score 0.06
- neoplasm · score 0.06
- central corneal thickness · score 0.06
- intraocular pressure measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95833-F1 | alphafold | PREDICTED | 93.96 | — |
Amino-acid sequence (236 residues)
MAETKLQLFV KASEDGESVG HCPSCQRLFM VLLLKGVPFT LTTVDTRRSP DVLKDFAPGS QLPILLYDSD AKTDTLQIED FLEETLGPPD FPSLAPRYRE SNTAGNDVFH KFSAFIKNPV PAQDEALYQQ LLRALARLDS YLRAPLEHEL AGEPQLRESR RRFLDGDRLT LADCSLLPKL HIVDTVCAHF RQAPIPAELR GVRRYLDSAM QEKEFKYTCP HSAEILAAYR PAVHPR
Explore Chloride intracellular channel protein 3 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets