About Pre-mRNA-splicing factor SYF2
Pre-mRNA-splicing factor SYF2 (SYF2) is a protein
from Homo sapiens identified by UniProt accession
O95926, 243 residues long.
MolForge cross-references it against 0 known binders and
41 disease associations.
Target properties
| Protein name | Pre-mRNA-splicing factor SYF2 |
|---|
| UniProt accession | O95926 |
|---|
| Gene | SYF2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 243 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (41)
Diseases linked to this target (Open Targets).
- hair shape measurement · score 0.34
- balding measurement · score 0.32
- alopecia · score 0.31
- androgenetic alopecia · score 0.30
- HbA1c measurement · score 0.26
- mean corpuscular hemoglobin concentration · score 0.21
- mean corpuscular volume · score 0.20
- neurodegenerative disease · score 0.18
- platelet crit · score 0.18
- mean corpuscular hemoglobin · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95926-F1 | alphafold | PREDICTED | 86.50 | — |
Amino-acid sequence (243 residues)
MAAIAASEVL VDSAEEGSLA AAAELAAQKR EQRLRKFREL HLMRNEARKL NHQEVVEEDK RLKLPANWEA KKARLEWELK EEEKKKECAA RGEDYEKVKL LEISAEDAER WERKKKRKNP DLGFSDYAAA QLRQYHRLTK QIKPDMETYE RLREKHGEEF FPTSNSLLHG THVPSTEEID RMVIDLEKQI EKRDKYSRRR PYNDDADIDY INERNAKFNK KAERFYGKYT AEIKQNLERG TAV
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