Integrin beta-like protein 1 (ITGBL1)

About Integrin beta-like protein 1

Integrin beta-like protein 1 (ITGBL1) is a protein from Homo sapiens identified by UniProt accession O95965, 494 residues long. MolForge cross-references it against 0 known binders and 79 disease associations.

Target properties

Protein name	Integrin beta-like protein 1
UniProt accession	O95965
Gene	ITGBL1
Organism	Homo sapiens
Length	494 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (79)

Diseases linked to this target (Open Targets).

body height · score 0.30
gonorrhea · score 0.10
neoplasm · score 0.10
hepatocellular carcinoma · score 0.09
pachyonychia congenita · score 0.08
drug use measurement · score 0.05
laryngotracheoesophageal cleft · score 0.05
hypertriglyceridemia 2 · score 0.05
cholesterol-ester transfer protein deficiency · score 0.05
cancer · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O95965-F1	alphafold	PREDICTED	84.46	—

Amino-acid sequence (494 residues)

MRPPGFRNFL LLASSLLFAG LSAVPQSFSP SLRSWPGAAC RLSRAESERR CRAPGQPPGA ALCHGRGRCD CGVCICHVTE PGMFFGPLCE CHEWVCETYD GSTCAGHGKC DCGKCKCDQG WYGDACQYPT NCDLTKKKSN QMCKNSQDII CSNAGTCHCG RCKCDNSDGS GLVYGKFCEC DDRECIDDET EEICGGHGKC YCGNCYCKAG WHGDKCEFQC DITPWESKRR CTSPDGKICS NRGTCVCGEC TCHDVDPTGD WGDIHGDTCE CDERDCRAVY DRYSDDFCSG HGQCNCGRCD CKAGWYGKKC EHPQSCTLSA EESIRKCQGS SDLPCSGRGK CECGKCTCYP PGDRRVYGKT CECDDRRCED LDGVVCGGHG TCSCGRCVCE RGWFGKLCQH PRKCNMTEEQ SKNLCESADG ILCSGKGSCH CGKCICSAEE WYISGEFCDC DDRDCDKHDG LICTGNGICS CGNCECWDGW NGNACEIWLG SEYP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards