Metalloproteinase inhibitor 1 (TIMP1)

About Metalloproteinase inhibitor 1

Metalloproteinase inhibitor 1 (TIMP1) is a protein from Homo sapiens identified by UniProt accession P01033, 207 residues long. MolForge cross-references it against 0 known binders and 1,346 disease associations.

Target properties

Protein name	Metalloproteinase inhibitor 1
UniProt accession	P01033
Gene	TIMP1
Organism	Homo sapiens
Length	207 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P01033-F1	alphafold	PREDICTED	89.61	—

Amino-acid sequence (207 residues)

MAPFEPLASG ILLLLWLIAP SRACTCVPPH PQTAFCNSDL VIRAKFVGTP EVNQTTLYQR YEIKMTKMYK GFQALGDAAD IRFVYTPAME SVCGYFHRSH NRSEEFLIAG KLQDGLLHIT TCSFVAPWNS LSLAQRRGFT KTYTVGCEEC TVFPCLSIPC KLQSGTHCLW TDQLLQGSEK GFQSRHLACL PREPGLCTWQ SLRSQIA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards