Lymphotoxin-alpha (LTA)

Homo sapiens — UniProt P01374

Gene: LTAHomo sapiensSwissProt reviewed

About Lymphotoxin-alpha

Lymphotoxin-alpha (LTA) is a protein from Homo sapiens identified by UniProt accession P01374, 205 residues long. MolForge cross-references it against 0 known binders and 885 disease associations.

Target properties

Protein nameLymphotoxin-alpha
UniProt accessionP01374
GeneLTA
OrganismHomo sapiens
Length205 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P01374-F1alphafoldPREDICTED83.41—

Amino-acid sequence (205 residues)

MTPPERLFLP RVCGTTLHLL LLGLLLVLLP GAQGLPGVGL TPSAAQTARQ HPKMHLAHST LKPAAHLIGD PSKQNSLLWR ANTDRAFLQD GFSLSNNSLL VPTSGIYFVY SQVVFSGKAY SPKATSSPLY LAHEVQLFSS QYPFHVPLLS SQKMVYPGLQ EPWLHSMYHG AAFQLTQGDQ LSTHTDGIPH LVLSPSTVFF GAFAL

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Quick facts

UniProtP01374
GeneLTA
OrganismHomo sapiens
Length205
Binders0
Diseases885
View on UniProt