Fatty acid-binding protein, heart (FABP3)

About Fatty acid-binding protein, heart

Fatty acid-binding protein, heart (FABP3) is a protein from Homo sapiens identified by UniProt accession P05413, 133 residues long. MolForge cross-references it against 0 known binders and 440 disease associations.

Target properties

Protein name	Fatty acid-binding protein, heart
UniProt accession	P05413
Gene	FABP3
Organism	Homo sapiens
Length	133 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (2)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (440)

Diseases linked to this target (Open Targets).

protein measurement · score 0.24
serum urea measurement · score 0.15
acute myocardial infarction · score 0.11
peripheral arterial disease · score 0.10
early-onset non-syndromic cataract · score 0.10
Sepsis · score 0.10
acute kidney failure · score 0.10
type 2 diabetes mellitus · score 0.09
neoplasm · score 0.09
alcohol dependence · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P05413-F1	alphafold	PREDICTED	96.20	—

Amino-acid sequence (133 residues)

MVDAFLGTWK LVDSKNFDDY MKSLGVGFAT RQVASMTKPT TIIEKNGDIL TLKTHSTFKN TEISFKLGVE FDETTADDRK VKSIVTLDGG KLVHLQKWDG QETTLVRELI DGKLILTLTH GTAVCTRTYE KEA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards