Fatty acid-binding protein, liver (FABP1)

About Fatty acid-binding protein, liver

Fatty acid-binding protein, liver (FABP1) is a protein from Homo sapiens identified by UniProt accession P07148, 127 residues long. MolForge cross-references it against 0 known binders and 318 disease associations.

Target properties

Protein name	Fatty acid-binding protein, liver
UniProt accession	P07148
Gene	FABP1
Organism	Homo sapiens
Length	127 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (1)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (318)

Diseases linked to this target (Open Targets).

serum alanine aminotransferase measurement · score 0.43
alkaline phosphatase measurement · score 0.39
blood protein measurement · score 0.38
C-reactive protein measurement · score 0.37
bilirubin measurement · score 0.30
aspartate aminotransferase to alanine aminotransferase ratio · score 0.27
hair color · score 0.13
sleep duration · score 0.13
acute kidney failure · score 0.12
hepatocellular carcinoma · score 0.11

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P07148-F1	alphafold	PREDICTED	95.09	—

Amino-acid sequence (127 residues)

MSFSGKYQLQ SQENFEAFMK AIGLPEELIQ KGKDIKGVSE IVQNGKHFKF TITAGSKVIQ NEFTVGEECE LETMTGEKVK TVVQLEGDNK LVTTFKNIKS VTELNGDIIT NTMTLGDIVF KRISKRI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards