Oleic acid

Drug profile

Also known as: 9Z-Octadecenoic acid, oleate, oleate sodium

FDA approved

Data last refreshed: 2026-11-10 (DrugCentral release 2024-11-01)

Open interactive profile (3D, safety, PGx)

Key facts

Oleic acid is a drug catalogued in DrugCentral. DrugCentral lists 19 molecular targets, including Fabp1, FABP4 and FABP1.

Molecular targets: Fabp1, FABP4, FABP1 and FABP5 (19 listed in DrugCentral).
Molecular formula: C18H34O2; molecular weight 282.47 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Contraindications (1)

Sensation Disturbance of Genitals

Mechanism & targets

Molecular targets (19)

Target	Gene	Action	Activity
Fatty acid-binding protein, liver	Fabp1	unknown	Ki 6.74
Fatty acid-binding protein, adipocyte	FABP4	unknown	Ki 6.73
Fatty acid-binding protein, liver	FABP1	unknown	Kd 6.70
Fatty acid-binding protein, epidermal	FABP5	unknown	Ki 6.61
Receptor-type tyrosine-protein kinase FLT3	FLT3	unknown	IC50 6.29
Peroxisome proliferator-activated receptor alpha	PPARA	unknown	IC50 6.22
Free fatty acid receptor 1	FFAR1	agonist	EC50 5.70
Peroxisome proliferator-activated receptor gamma	PPARG	unknown	IC50 5.39
Peroxisome proliferator-activated receptor delta	PPARD	unknown	IC50 5.28
Fatty-acid amide hydrolase 1	FAAH	unknown	Ki 5.22
Tyrosine-protein phosphatase non-receptor type 1	PTPN1	unknown	IC50 5.21
Telomerase reverse transcriptase	TERT	unknown	IC50 5.07
Free fatty acid receptor 4	FFAR4	agonist	EC50 4.70
Seed linoleate 13S-lipoxygenase-1	LOX1.1	unknown	Ki 4.66
DNA topoisomerase 1	TOP1	unknown	IC50 4.51
Aromatase	CYP19A1	unknown	IC50 4.49
Nuclear receptor subfamily 4 group A member 2	NR4A2	unknown	Kd 4.30
Tissue factor	F3	unknown	IC50 4.10
NAD-dependent protein deacetylase sirtuin-6	SIRT6	unknown	EC50 4.05

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
—	FDA	—	—

Chemical structure

Molecular formula	C₁₈H₃₄O₂
Molecular weight	282.47 g/mol
CAS number	112-80-1
InChIKey	ZQPPMHVWECSIRJ-KTKRTIGZSA-N
PubChem CID	445639

CCCCCCCC\C=C/CCCCCCCC(O)=O

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Oleic acid work?

Its molecular targets in DrugCentral include Fabp1, FABP4, FABP1 and FABP5.

What is the chemical formula of Oleic acid?

Oleic acid has the molecular formula C18H34O2 and a molecular weight of 282.47 g/mol.

Browse: all drugs starting with O · drug guides by category · protein targets A–Z.

Sources

DrugCentral drug card 3400 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
ChEMBL CHEMBL8659 — compound record and bioactivity
PubChem CID 445639 — chemical identifiers
DrugBank DB04224 — drug record
FDA UNII 2UMI9U37CP — substance identity
DailyMed: FDA labels for Oleic acid — current prescribing information (label search)
UniProt P15090 (FABP4) — target protein
UniProt P07148 (FABP1) — target protein
UniProt Q01469 (FABP5) — target protein
UniProt P36888 (FLT3) — target protein
UniProt Q07869 (PPARA) — target protein
UniProt O14842 (FFAR1) — target protein

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.