Fatty acid-binding protein 5 (FABP5)

About Fatty acid-binding protein 5

Fatty acid-binding protein 5 (FABP5) is a protein from Homo sapiens identified by UniProt accession Q01469, 135 residues long. MolForge cross-references it against 0 known binders and 201 disease associations.

Target properties

Protein name	Fatty acid-binding protein 5
UniProt accession	Q01469
Gene	FABP5
Organism	Homo sapiens
Length	135 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (1)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (201)

Diseases linked to this target (Open Targets).

pathological myopia · score 0.24
neoplasm · score 0.11
psoriasis · score 0.11
hepatocellular carcinoma · score 0.11
cancer · score 0.09
experimental autoimmune encephalomyelitis · score 0.08
chronic obstructive pulmonary disease · score 0.08
triple-negative breast cancer · score 0.08
non-small cell lung carcinoma · score 0.07
gonorrhea · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q01469-F1	alphafold	PREDICTED	96.32	—

Amino-acid sequence (135 residues)

MATVQQLEGR WRLVDSKGFD EYMKELGVGI ALRKMGAMAK PDCIITCDGK NLTIKTESTL KTTQFSCTLG EKFEETTADG RKTQTVCNFT DGALVQHQEW DGKESTITRK LKDGKLVVEC VMNNVTCTRI YEKVE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards