Spermatid nuclear transition protein 1 (TNP1)

About Spermatid nuclear transition protein 1

Spermatid nuclear transition protein 1 (TNP1) is a protein from Homo sapiens identified by UniProt accession P09430, 55 residues long. MolForge cross-references it against 0 known binders and 167 disease associations.

Target properties

Protein name	Spermatid nuclear transition protein 1
UniProt accession	P09430
Gene	TNP1
Organism	Homo sapiens
Length	55 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (167)

Diseases linked to this target (Open Targets).

body height · score 0.40
glomerular filtration rate · score 0.37
pulse pressure measurement · score 0.37
breast carcinoma · score 0.36
refractive error measurement · score 0.36
creatinine measurement · score 0.35
appendicular lean mass · score 0.34
lean body mass · score 0.34
body fat percentage · score 0.33
breast cancer · score 0.31

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P09430-F1	alphafold	PREDICTED	62.14	—

Amino-acid sequence (55 residues)

MSTSRKLKSH GMRRSKSRSP HKGVKRGGSK RKYRKGNLKS RKRGDDANRN YRSHL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards