Uncharacterized serine/threonine-protein kinase…

About Uncharacterized serine/threonine-protein kinase SBK3

Uncharacterized serine/threonine-protein kinase SBK3 (SBK3) is a protein from Homo sapiens identified by UniProt accession P0C264, 359 residues long. MolForge cross-references it against 0 known binders and 2 disease associations.

Target properties

Protein name	Uncharacterized serine/threonine-protein kinase SBK3
UniProt accession	P0C264
Gene	SBK3
Organism	Homo sapiens
Length	359 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (6)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (2)

Diseases linked to this target (Open Targets).

drug use measurement · score 0.03
Colon Sessile Serrated Adenoma/Polyp · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0C264-F1	alphafold	PREDICTED	85.82	—

Amino-acid sequence (359 residues)

MERRASETPE DGDPEEDTAT ALQRLVELTT SRVTPVRSLR DQYHLIRKLG SGSYGRVLLA QPHQGGPAVA LKLLRRDLVL RSTFLREFCV GRCVSAHPGL LQTLAGPLQT PRYFAFAQEY APCGDLSGML QERGLPELLV KRVVAQLAGA LDFLHSRGLV HADVKPDNVL VFDPVCSRVA LGDLGLTRPE GSPTPAPPVP LPTAPPELCL LLPPDTLPLR PAVDSWGLGV LLFCAATACF PWDVALAPNP EFEAFAGWVT TKPQPPQPPP PWDQFAPPAL ALLQGLLDLD PETRSPPLAV LDFLGDDWGL QGNREGPGVL GSAVSYEDRE EGGSSLEEWT DEGDDSKSGG RTGTDGGAP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Uncharacterized serine/threonine-protein kinase SBK3 (SBK3)