Thymosin beta-15A (TMSB15A)

About Thymosin beta-15A

Thymosin beta-15A (TMSB15A) is a protein from Homo sapiens identified by UniProt accession P0CG34, 45 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.

Target properties

Protein name	Thymosin beta-15A
UniProt accession	P0CG34
Gene	TMSB15A
Organism	Homo sapiens
Length	45 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (31)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.42
medulloblastoma · score 0.05
central nervous system cancer · score 0.04
triple-negative breast cancer · score 0.04
atypical teratoid rhabdoid tumor · score 0.03
primitive neuroectodermal tumor · score 0.02
glioblastoma multiforme · score 0.02
astrocytoma · score 0.02
carcinoma · score 0.02
oligodendroglioma · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0CG34-F1	alphafold	PREDICTED	71.62	—

Amino-acid sequence (45 residues)

MSDKPDLSEV EKFDRSKLKK TNTEEKNTLP SKETIQQEKE CVQTS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards