About Serum amyloid A-2 protein
Serum amyloid A-2 protein (SAA2) is a protein
from Homo sapiens identified by UniProt accession
P0DJI9, 122 residues long.
MolForge cross-references it against 0 known binders and
43 disease associations.
Target properties
| Protein name | Serum amyloid A-2 protein |
|---|
| UniProt accession | P0DJI9 |
|---|
| Gene | SAA2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 122 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (43)
Diseases linked to this target (Open Targets).
- serum amyloid A-1 protein measurement · score 0.25
- blood protein measurement · score 0.24
- cerebrospinal fluid biomarker measurement · score 0.06
- ulcerative colitis · score 0.06
- protein measurement · score 0.06
- Crohn's disease · score 0.04
- serum amyloid A protein measurement · score 0.04
- central nervous system cancer · score 0.04
- esophageal adenocarcinoma · score 0.03
- hepatocellular carcinoma · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P0DJI9-F1 | alphafold | PREDICTED | 93.86 | — |
Amino-acid sequence (122 residues)
MKLLTGLVFC SLVLSVSSRS FFSFLGEAFD GARDMWRAYS DMREANYIGS DKYFHARGNY DAAKRGPGGA WAAEVISNAR ENIQRLTGRG AEDSLADQAA NKWGRSGRDP NHFRPAGLPE KY
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