About Protein SETSIP
Protein SETSIP (SETSIP) is a protein
from Homo sapiens identified by UniProt accession
P0DME0, 292 residues long.
MolForge cross-references it against 0 known binders and
11 disease associations.
Target properties
| Protein name | Protein SETSIP |
|---|
| UniProt accession | P0DME0 |
|---|
| Gene | SETSIP |
|---|
| Organism | Homo sapiens |
|---|
| Length | 292 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (11)
Diseases linked to this target (Open Targets).
- intellectual disability, autosomal dominant 58 · score 0.34
- serum alanine aminotransferase measurement · score 0.05
- asthma · score 0.03
- allergic disease · score 0.03
- lymphatic malformation 8 · score 0.03
- anencephaly 1 · score 0.03
- spina bifida-hypospadias syndrome · score 0.03
- monocyte count · score 0.03
- mean corpuscular hemoglobin concentration · score 0.03
- HbA1c measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P0DME0-F1 | alphafold | PREDICTED | 78.00 | — |
Amino-acid sequence (292 residues)
MAPKRQSPLP LQKKKPRPPP ALGLEETSAS AGLPKKGEKE QQEAIEHIDE VQNEIDRLNE QDSEEILKVE QKYNKLRQPF FQKRSELIAK IPNFGVTTFV NHPQVSSLLG EEDEEALHYL TKVEVTEFED IKSGYRIDFY FDENPYFENK VFSKEFHLNE SGDPSSKSTK IKWKSGKDVT KRSSQTQNKA SRKRQHEEPE SFFTWFTDHS DAGADELEEV IKDDIWPNPL QYYLVPDMDD EEGGEDDDDD DDDGDEGEEE LEDIDEGDED EGEEDEDDDE GEEGEEDEGE DD
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