Sulfotransferase 1A3 (SULT1A3)

About Sulfotransferase 1A3

Sulfotransferase 1A3 (SULT1A3) is a protein from Homo sapiens identified by UniProt accession P0DMM9, 295 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.

Target properties

Protein name	Sulfotransferase 1A3
UniProt accession	P0DMM9
Gene	SULT1A3
Organism	Homo sapiens
Length	295 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (38)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.36
FEV/FVC ratio · score 0.04
Hepatic veno-occlusive disease - immunodeficiency · score 0.04
congenital dyserythropoietic anemia type 2 · score 0.04
Congenital dyserythropoietic anemia type II · score 0.04
Senior-Boichis syndrome · score 0.04
sclerosing cholangitis · score 0.03
hemolytic anemia due to glucophosphate isomerase deficiency · score 0.03
progressive familial intrahepatic cholestasis type 3 · score 0.03
non-spherocytic hemolytic anemia due to hexokinase deficiency · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0DMM9-F1	alphafold	PREDICTED	96.56	—

Amino-acid sequence (295 residues)

MELIQDTSRP PLEYVKGVPL IKYFAEALGP LQSFQARPDD LLINTYPKSG TTWVSQILDM IYQGGDLEKC NRAPIYVRVP FLEVNDPGEP SGLETLKDTP PPRLIKSHLP LALLPQTLLD QKVKVVYVAR NPKDVAVSYY HFHRMEKAHP EPGTWDSFLE KFMAGEVSYG SWYQHVQEWW ELSRTHPVLY LFYEDMKENP KREIQKILEF VGRSLPEETM DFMVQHTSFK EMKKNPMTNY TTVPQELMDH SISPFMRKGM AGDWKTTFTV AQNERFDADY AEKMAGCSLS FRSEL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards