Sulfotransferase 1A4 (SULT1A4)

About Sulfotransferase 1A4

Sulfotransferase 1A4 (SULT1A4) is a protein from Homo sapiens identified by UniProt accession P0DMN0, 295 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.

Target properties

Protein name	Sulfotransferase 1A4
UniProt accession	P0DMN0
Gene	SULT1A4
Organism	Homo sapiens
Length	295 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (38)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.37
Hepatic veno-occlusive disease - immunodeficiency · score 0.04
congenital dyserythropoietic anemia type 2 · score 0.04
Congenital dyserythropoietic anemia type II · score 0.04
Senior-Boichis syndrome · score 0.04
sclerosing cholangitis · score 0.03
hemolytic anemia due to glucophosphate isomerase deficiency · score 0.03
progressive familial intrahepatic cholestasis type 3 · score 0.03
non-spherocytic hemolytic anemia due to hexokinase deficiency · score 0.03
idiopathic hypereosinophilic syndrome · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0DMN0-F1	alphafold	PREDICTED	96.56	—

Amino-acid sequence (295 residues)

MELIQDTSRP PLEYVKGVPL IKYFAEALGP LQSFQARPDD LLINTYPKSG TTWVSQILDM IYQGGDLEKC NRAPIYVRVP FLEVNDPGEP SGLETLKDTP PPRLIKSHLP LALLPQTLLD QKVKVVYVAR NPKDVAVSYY HFHRMEKAHP EPGTWDSFLE KFMAGEVSYG SWYQHVQEWW ELSRTHPVLY LFYEDMKENP KREIQKILEF VGRSLPEETM DFMVQHTSFK EMKKNPMTNY TTVPQELMDH SISPFMRKGM AGDWKTTFTV AQNERFDADY AEKMAGCSLS FRSEL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards